Schedule: Detroit Lions
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| Home Team | Away Team | Home Score | Away Score | W - L | Game Date | Game Won |
|---|---|---|---|---|---|---|
| Detroit Lions | Los Angeles Rams | 26 | 20 | 1 - 0 | 09-08-2024 | 1 |
| Detroit Lions | Tampa Bay Buccaneers | 16 | 20 | 1 - 1 | 09-15-2024 | 0 |
| Arizona Cardinals | Detroit Lions | 13 | 20 | 2 - 1 | 09-22-2024 | 1 |
| Detroit Lions | Seattle Seahawks | 42 | 29 | 3 - 1 | 09-30-2024 | 1 |
| Dallas Cowboys | Detroit Lions | 9 | 47 | 4 - 1 | 10-13-2024 | 1 |
| Minnesota Vikings | Detroit Lions | 29 | 31 | 5 - 1 | 10-20-2024 | 1 |
| Detroit Lions | Tennessee Titans | 52 | 14 | 6 - 1 | 10-27-2024 | 1 |
| Green Bay Packers | Detroit Lions | 14 | 24 | 7 - 1 | 11-03-2024 | 1 |
| Houston Texans | Detroit Lions | 23 | 26 | 8 - 1 | 11-10-2024 | 1 |
| Detroit Lions | Jacksonville Jaguars | 52 | 6 | 9 - 1 | 11-17-2024 | 1 |
| Indianapolis Colts | Detroit Lions | 6 | 24 | 10 - 1 | 11-24-2024 | 1 |
| Detroit Lions | Chicago Bears | 23 | 20 | 11 - 1 | 11-28-2024 | 1 |
| Detroit Lions | Green Bay Packers | 34 | 31 | 12 - 1 | 12-05-2024 | 1 |
| Detroit Lions | Buffalo Bills | 42 | 48 | 12 - 2 | 12-15-2024 | 0 |
| Chicago Bears | Detroit Lions | 17 | 34 | 13 - 2 | 12-22-2024 | 1 |
| San Francisco 49ers | Detroit Lions | 34 | 40 | 14 - 2 | 12-30-2024 | 1 |
| Detroit Lions | Minnesota Vikings | 31 | 9 | 15 - 2 | 01-05-2025 | 1 |
| Detroit Lions | Washington Commanders | 31 | 45 | 15 - 3 | 01-18-2025 | 0 |